The story follows Rebecca Carlson (Madonna), who is accused of killing her wealthy, elderly lover by having sex with him until he suffered a fatal heart attack. Prosecutor Robert Garrett (Joe Mantegna) claims she intentionally used her sexuality as a weapon for financial gain.
Rebecca hires defense attorney Frank Dulaney (Willem Dafoe), but their professional relationship quickly turns into a dangerous sexual obsession. As the trial unfolds, the line between seduction and manipulation blurs, and Frank becomes entangled in Rebecca’s web of deceit, unsure if she’s innocent or a calculating killer.