Dr. Miranda Grey (played by Halle Berry) is a brilliant criminal psychologist working at a women’s penitentiary. One night, after a car accident during a storm, she sees a mysterious girl standing in the road—and suddenly blacks out.

She wakes up to find herself imprisoned in her own facility, accused of brutally murdering her husband (played by Charles S. Dutton), with no memory of the crime. As she tries to unravel the truth, she begins experiencing terrifying paranormal events and ghostly visions, particularly of a young girl who seems to be trying to communicate with her.

As Miranda investigates, she realizes she may have been possessed or manipulated by a spirit trying to reveal dark secrets about her husband's past—and more victims.